Process Development Scientist - Oligonucleotide Chemistry
Process Development Scientist - Oligonucleotide Chemistry
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Not Disclosed
Salary Not Disclosed
1 Vacancy
Job Description
This is an exciting time to join the Eurofins Genomics LLC process development group. The company is rapidly expanding oligonucleotide manufacturing to support the increasing demand of molecular diagnostics. Process Development Scientist will work directly with some of the biggest companies in life sciences to manufacture and develop oligonucleotides (oligos) and support ever evolving needs. Eurofins Genomics LLC is a leading manufacturer of Oligonucleotide primers/probes/assays in addition to being a key supplier of oligos for other diagnostic applications.
The Process Development Scientist will be an owner in area of expertise (oligonucleotide synthesis purification organic chemistry and quality control). This position reports directly to the Director of Oligonucleotide Chemistry
- Handson expertise in preparing chromatography and analytical techniques throughout the product development lifecycle from early research to onmarket support diagnostics
- Demonstrated experience purifying analyzing and characterizing complex oligonucleotides and related analytical methods.
- Ability to develop innovative analytical methods for reagents and assay performance applicable in R&D and Operations; supporting scaleup and launch efforts
- Ability to design and execute advanced troubleshooting experiments in coordination with collaborators; demonstrated experience developing creative assays to understand and detect system defects
- Ability to support documentation transfer specifically of prototype methods and documentation from research to development and manufacturing
- Serve as a subject matter expert and provide expertise across R&D departments (oligo synthesis & purification assay development) and operations
- Document all assays and results in a standardized accurate traceable and timely manner
- Perform mentor type duties including the training of more junior employees
- Adhering to cGMP/cGLP documentation procedures according to FDA specifications
- HPLC method development for specific DNA/RNA modifications scales lengths and purity
- Customization of method and mobile phases to maximize yields while maintaining quality
- Develop new downstream workflows for automated larger scale purification process
- Develop and implement other purification processes (PAGE Cartridge etc) that expand portfolio for purification
Qualifications :
- BS minimum 5 years/MS/PhD in Chemistry Biochemistry or a related field
- Manufacturing experience and comfortability being in a production role
- Work with nucleic acids
- Experience with oligonucleotide synthesis
- A positive attitude strong work ethic and ability to work both independently and in constructive groups
Additional Information :
Schedule:
- MondayFriday 8:00am5:00pm
What we offer:
- Excellent full time benefits including comprehensive medical coverage dental and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
Eurofins is a M/F Disabled and Veteran Equal Employment Opportunity and Affirmative Action employer.
Remote Work :
No
Employment Type :
Fulltime
Employment Type
Full-time
