Senior Scientist Biologics Purification and Characterization
Senior Scientist Biologics Purification and Characterization
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1 Vacancy
Job Description
Are you ready to make a difference in the world of biologics drugdiscovery
AbbVies Biologics Discovery Sciences group is on the hunt for a passionate and skilled Senior Scientist to join our innovative team in North Chicago IL. If youre a creative problem solver with an eye for detail and a drive to advance biologics purification processes we want you to be part of our journey.
About the Role:
As a Senior Scientist in our dynamic core team you will focus on the purification of bispecific candidates ensuring they exhibit suitable purity and characteristics to support advancement into in vitro studies (i.e. druglike property assays binding cellbased assays etc) and in vivo studies (i.e. efficacy nonGLP NHP PK DRF etc). We are looking for an independent driven scientist to champion chromatography efforts to overcome the challenges associated with purifying bispecific proteins. Your expertise will drive the design and execution of process development strategies that address production liabilities and ensure future process scalability. You will engage in intensive analytical characterization of molecules (endproducts/processintermediates) and extensive methods development to identify and remove process and product relatedimpurities.
Key Responsibilities:
- Purification of bispecific candidates at scales ranging from 1g to 200g.
- Design and execute process development strategies to overcome purification challenges.
- Perform intensive analytical characterization of molecules endproducts byproducts and process intermediates.
- Collaborate with crossfunctional teams to advance drug discovery projects.
- Document and report data with precision ensuring rigorous scientific communication.
Qualifications :
Qualifications:
Position will be hired based on level of experience Senior Scientist I or Senior Scientist II
- BS MS or Ph.D. in Biochemistry Biophysics Biochemical Engineering or a related field with typically 1012 years (BS) 810 years (MS) or 04 years (Ph.D.).
- Expertise in all standard bioprocess steps and preparative chromatography techniques including software systems (Unicorn Chromeleon Empower).
- Expertise in AKTA chromatography systems.
- Understanding of molecular and posttranslational protein attributes and their role in protein function.
- Strong problemsolving and analytical skills to address issues such as solubility and aggregation.
- Excellent communication and presentation skills.
- Experience in instrumentation automation is preferred.
- Lifting carrying pushing or pulling weights of more than 20 lbs/9 kgs is required.
Drive innovation. Inspire change. Make a difference.
Embark on a rewarding career with AbbVie and help us transform lives through the power of biologics discovery.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our shortterm incentive programs.
This job maybe eligible to participate in our longterm incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race color religion national origin age sex (including pregnancy) physical or mental disability medical condition genetic information gender identity or expression sexual orientation marital status status as a protected veteran or any other legally protected group status.
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Remote Work :
No
Employment Type :
Fulltime
Employment Type
Full-time
