Postdoctoral Researcher
Postdoctoral Researcher
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Job Description
Union: NonUnion
Site: Princess Margaret Cancer Research Tower
Department: Research
Reports to: Dr. Steven Chan Principal Investigator
Work Model: OnSite
Grade: V0:90
Hours: 37.5 hours per week
Salary: $53303 $79954 annually (To commensurate with experience and consistent with UHN compensation policy)
Shifts: Day
Status: Temporary Fulltime
Closing Date: January 18 2025
Position Summary
We are seeking an exceptional Postdoctoral Researcher to join our team investigating dependencies associated with clonal hematopoiesis and acute myeloid leukemia and developing innovative therapeutic strategies targeting these conditions. The Chan Laboratory is located at the Princess Margaret Cancer Centre in Toronto Canada with full access to stateoftheart facilities in Torontos Discovery District. The lab employs advanced genetic screening and CRISPR/Cas9 genome editing tools to identify and investigate specific gene dependencies that drive clonal hematopoiesis and acute myeloid leukemia (AML) progression in mouse models.
Duties
- Design and Conduct Experiments: Develop and execute experimental protocols to investigate the biology of leukemia stem cells and mechanisms of clonal hematopoiesis using advanced molecular and cellular techniques
- Data Analysis and Interpretation: Perform comprehensive data analysis including bioinformatics and statistical analysis to interpret experimental results and draw meaningful conclusions.
- Stem Cell Isolation and Characterization: Isolate and characterize hematopoietic stem cells and leukemia stem cells from primary patient samples or animal models utilizing techniques such as flow cytometry cell sorting and other stem cell assays.
- Collaboration and Teamwork: Work closely with other researchers including graduate students and other postdoctoral fellows to support ongoing projects and foster a collaborative research environment.
- Literature Review and Research Development: Stay updated on recent literature and advancements in leukemia research identify new research opportunities and propose novel hypotheses to explore within the labs focus area.
- Manuscript and Grant Writing: Prepare research findings for publication in peerreviewed journals and contribute to writing grant applications to secure additional funding for research projects.
- Mentorship and Training: Mentor junior researchers including graduate and undergraduate students by providing guidance on experimental design lab techniques and data analysis.
- Presentation of Findings: Present research findings at lab meetings seminars and national or international conferences to share progress and gain feedback from the scientific community.
Qualifications :
- PhD must be obtained within the previous 5 years in molecular biology genetics biochemistry or related field
- Strong background in cancer biology particularly hematological malignancies
- Expertise in molecular biology genetic screening and genome editing techniques
- Experience in flow cytometry tissue culture or working with animals is an asset.
- Excellent analytical and problemsolving skills
- Proven track record of scientific publications
Additional Information :
Why join UHN
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world UHN offers a wide range of benefits programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor allowing you to find value where it matters most to you now and throughout your career at UHN.
- Competitive offer packages
- Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP )
- Close access to Transit and UHN shuttle service
- A flexible work environment
- Opportunities for development and promotions within a large organization
- Additional perks (multiple corporate discounts including: travel restaurants parking phone plans auto insurance discounts onsite gyms etc.)
Current UHN employees must have successfully completed their probationary period have a good employee record along with satisfactory attendance in accordance with UHNs attendance management program to be eligible for consideration.
All applications must be submitted before the posting close date.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading inaccurate or incorrect UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest however only those selected for further consideration will be contacted.
Remote Work :
No
Employment Type :
Contract
Employment Type
Contract
