Scientist I Downstream Process Development

Job Title Scientist I (Downstream Process Development)

Location 75 Shoreway Road Suite A San Carlos CA 94070

Duration 6 Months (Possible extension for long term)

Job Description

Summary: The Process Development team is seeking a talented highly motivated Scientist I to work on the purification of therapeutic antibody drug candidates from human and mouse immune repertoires. The successful candidate will provide downstream process development and material generation support within the companys Process Development team.

FAQ

• The work schedule will be MonFri 40 hours with some flexibility but approximately 8 am 5 pm. This will be benchscale work with antibody purification from human and mouse models and will be primarily benchscale lab work (Likely start date in January due to holidays).
• Ideal candidate will have antibody purification or other protein purification experience using FPLC or HPLC (affinity ion exchange or hydrophobic chromatography) and candidate really needs to have experience with AKTA for chromatography systems.
• Interview process will be a 30 minute virtual / phone interview with the hiring manager and then round 2 will be 1/2 day onsite with the team. This position is onsite with mostly lab work and may allow for some hybrid work to complete paperwork but this is mostly an inperson lab position.

Primary responsibilities for role:

• Development optimize and scaleup purification processes for biologics candidates to support early stage development
• Analyse and interpret data to drive technical understanding meet project targets and objectives problem solve and make recommendations that drive efficiency knowledge and manage risk
• Collaborate closely with other functional areas involved in antibody therapeutics development including upstream process development analytical development project management and crossfunctional partners
• Work effectively with external collaborators and CROs
• Coordinate activities with functional groups and project teams
• Discuss experiments and data to project team members
• Develop write and review standard operating protocols and other technical documents
• May act as a lead for assigned projects or team
• Mentor and train other technical staff

Knowledge Skills and Abilities:

• Experience in protein purification techniques especially chromatography; antibody purification experience preferred
• Proficient in writing methods and operating AKTA chromatographic instruments (such as AKTA Avant AKTA Purifier AKTA Pure AKTA Ready or similar)
• Strong scientific understanding and logical thinking
• Ability to train others in basic laboratory techniques and equipment operation
• Proficiency in analytical method development and analytical method validation
• Demonstrate flexibility and problemsolving activities

Education

• Bachelor Experience 4 years Equivalency Masters with 2 years of experience

OnBoarding Requirements:

• Address to Criminal History (7 year) Address to Federal Criminal History (7 year) AKA Names Provided (up to 9)
• Education Verification
• Employment Verification (up to 3 years or last 3 employers)
• Social Security Address/Alias Trace Office of Inspector General Sanctions (OIG) / System for Award Mgmt. (SAM) Exclusion (part of FACIS I) National Criminal Database search 10 Panel Rapid Drug Screen (Excluding THC)