Laboratory Technician Pre-Clinical Vector Manufacturing
Laboratory Technician Pre-Clinical Vector Manufacturing
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Job Description
Meghna at
Hema at
Location: Research Triangle Park NC
Duration: 6 Months
About the role:
The Laboratory Technician PreClinical Vector Manufacturing reporting to the Vector Manufacturing Team Lead is responsible for supporting routine laboratory operations related to manufacturing researchgrade recombinant Adenoassociated virus (rAAV) vectors. The rAAV vectors manufactured support capsid technology development intellectual property portfolio and progression of internal and external earlystage gene therapy programs.
The Laboratory Technician PreClinical Vector Manufacturing will Assist in the organization preparation and maintenance of the vector manufacturing laboratory. The position is responsible for maintaining operational readiness of the vector manufacturing laboratory by assisting in routine laboratory activities such as solution preparation process staging daily equipment checks and inventory management.
The successful candidate will have at minimum an Associates degree in in a relevant field of study or relevant experience operating in a laboratory or biological manufacturing environment. This opportunity will be based in our Research Triangle Park (RTP) North Carolina headquarters.
Perform buffer and solution preparation activities in accordance with established procedures
Monitor and maintain buffer and solution inventory levels to support daily lab activities
Monitor biohazardous and liquid waste containers throughout the day and ensure they are changed out regularly. Organize pickup and disposal as needed in collaboration with facilities waste management team.
Assist with cleaning of lab and equipment (incubators biosafety cabinets centrifuges etc.) before and after each manufacturing run
Clean and stock labware in accordance with established procedures. Ensure that labware inventory levels are maintained to support daily laboratory operations.
Operate autoclave in accordance with established procedures
Assist with operation and maintenance of laboratory equipment including daily calibrations and cleanings to ensure operational readiness. Keep work surfaces clean and orderly.
Monitor inventory levels of laboratory supplies (reagents consumables buffers etc.) and ensure minimum inventory levels are maintained.
Perform weekly sampling of water system and submit for analytical testing
Support production activities including aliquoting buffers system setup and plasmid staging and reconciliation
Assist with sample chain of custody including login and transfer of samples to analytical teams for testing
Assist with shipment and receipt of materials between sites including sample aliquoting and compiling samplespecific documentation to accompany material shipments
Understand and adhere to laboratory safety requirements follow environmental health and safety guidelines to properly dispose of samples and waste.
Conducts work in accordance with established SOPs and ensures documentation is executed in a timely and professional manner in accordance with good documentation practices (GDP)
As needed collect data and prepare for analysis and interpretation.
Perform other labrelated duties as assigned.
AS in Biotechonlogy/Biopharmaceutical Technology Engineering biology microbiology chemistry biochemistry or related field with 2 years of relevant laboratory experience or equivalent combination of education and experience
Knowledge of lab safety procedures and processes
Excellent written and verbal communication and record keeping skills (with strong attention to detail) is required
Good organizational skills
Familiarity with upstream or downstream process operations such as cell culture centrifugation depth filtration tangentialflow filtration and/or chromatography with expertise in at least one functional area is preferred
Be comfortable with working and learning in a fastpaced laboratory environment.
Able to follow instructions and strictly follow procedures
Ability to effectively communication with leadership and coworkers to ensure that task assignments are understood and delays or problems are communicated in an efficient and timely manner
Familiarity with ELN or LIMS systems is a plus
Proficient in Microsoft Excel and Word
Experience with BSL2 microbial culture mammalian cell culture
Selfmotivation a strong sense of accountability willingness to participate in developing and maintaining a strong positive and supporting work climate
Have a serviceoriented and quality mindset/attitude.
Experience maintaining documentation in accordance with good documentation practices is preferred
About us: DivIHN the IT Asset Performance Services organization provides Professional Consulting Custom Projects and Professional Resource Augmentation services to clients in the MidWest and beyond. The strategic characteristics of the organization are Standardization Specialization and Collaboration. DivIHN is an equal opportunity employer. DivIHN does not and shall not discriminate against any employee or qualified applicant on the basis of race color religion (creed) gender gender expression age national origin (ancestry) disability marital status sexual orientation or military status.
Employment Type
Full Time
