Incorporated in 1993 Syngene International Ltd. is an innovationfocused global discovery development and manufacturing organization providing integrated scientific services to the pharmaceutical biotechnology nutrition animal health consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as BristolMyers Squibb Baxter Amgen GSK Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240 strong team of scientists who work with clients from around the world to solve their scientific problems improve R&D productivity speed up time to market and lower the cost of innovation.
Job Purpose (12 Lines)
To lead a team of scientists for developing preclinical & clinical formulations of new chemical entities (NCEs).
Key Responsibilities: (Maximum 58 Points)
Provide scientific leadership within Pharmaceutics domain to identify clinically developable drug candidates which includes:
Lead projects & guide the team on development of different formulation(s) like solution suspension tablet capsule for:
Preclinical studies
GLP toxicology studies
Phase I (FIH) & Phase II clinical studies
Good understanding of drug degradation mechanisms and experimental analysis is preferred.
Competency in understanding & assessing biopharmaceutics risks towards potential solubility & absorption issues with NCEs which includes utilization of various in vitro in silico & in vivo tools.
Good understanding of various novel drug delivery systems (NDDS) to improve oral bioavailability of a challenging NCE.
Fair understanding of analytical principles to characterize drug product(s).
Ability to investigate processinduced solidstate transformation(s) while developing drug product using crystalline salt or amorphous solid dispersion forms of drug substance.
Knowledge of scientific principles and practices of other pharmaceutical development functional areas such as Chemical Process Research Drug Metabolism and Pharmacokinetics Drug Safety Evaluation is desired.
Educational Qualification
Ph.D. (full time) / PostDoctorate in Pharmaceutics / Industrial Pharmacy / Pharmaceutical Technology or related field(s)
Technical/functional Skills: (Maximum 46 Points)
Pharmaceutics
Physical Pharmacy
Dosage Form Design
Drug Delivery
Chemical Degradation
Biopharmaceutics
Experience
917 years of relevant industrial experience
Behavioral Skills
Demonstrated ability of leading/managing a group of scientists for project accountabilities.
Experience of working with matrix teams in a complex dynamic environment to effectively achieve objectives.
Excellent written & oral communication skills and strong interpersonal & team working skills.
Demonstrate crossfunctional / crosssite collaboration towards project deliverables.
Train coach & mentor team members for higher standard of deliverables.
Equal Opportunity Employer
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age color national origin citizenship status physical or mental disability race religion creed gender sex sexual orientation gender identity and/or expression genetic information marital status status with regard to public assistance veteran status or any other characteristic protected by applicable legislation or local law. In addition Syngene will provide reasonable accommodations for qualified individuals with disabilities.
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