X Ray Crystallographer
X Ray Crystallographer
Posted on :
16-10-2024
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Job Description
Job Description:
We seek an enthusiastic scientist capable of solving the challenges associated with leadingedge discoveries. The successful candidate will integrate into an international and multidisciplinary team of scientists engage in different research areas and work crossfunctionally with the IO and Virology team to leverage crystallography to solve key molecular structures produce highquality proteins and contribute to the development and advancement of novel therapeutic strategies.
This scientist is the vanguard of our R and amp;D efforts capable of adapting to any situation and responding swiftly to changing conditions. From urgent research studies to critical experiments this team member executes efficiently and effectively.
Key Responsibilities:
- Leverage crystallography experience to solve crystal structures of key targets/molecules including protein crystallography initial screening crystal quality optimization data collection and structure determination
- Work crossfunctionally with IO / Virology teams to produce proteins including designing the methodology and performing the purification of proteins of therapeutic interest to provide highquality material for the advancement of drug discovery campaigns
- Collaborates with biologists biophysicists biochemists structural biologists and medicinal chemists to develop comprehensive approaches to ensure target viability and address specific project needs
- Establish protocols to characterize target proteins for small molecule
Education and Experience:
- Master / PhD degree in Structural Biology / Protein Biochemistry
- 35 years of work experience as a bench scientist in industry (e.g. biotech pharma)
- Experience Protein Purification for different expression systems using multiple techniques
- Preference will be given to candidates who have direct experience in enzymology and crystallization techniques (cocrystallization seeding crossseeding soaking harvesting and freezing)
- Familiar with chemistry and protein computational techniques
- Champion a can do attitude and flexibility to adjust as R and amp;D priorities shift
Employment Type
Full Time
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