Predoctoral researcher Therapeutics and innovations in neuropediatrics and other paediatric rare diseases tin-rd group
Predoctoral researcher Therapeutics and innovations in neuropediatrics and other paediatric rare diseases tin-rd group
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Job Description
The group aim is to promote the implementation of advanced therapies and innovative therapies of high technological complexity in pediatric rare diseases specifically in Neurological ultrarare diseases that impact the motor development of children and adolescents.
The group aims to promote precision diagnosis and precision medicine in children with severe impairment in motor development in order to improve quality of life from early life. We focus our research in three main objectives: (1) to perform a precise genetic diagnosis of ultrarare diseases causing disorders of motor development in childhood and adolescence; (2) to develop programs for a personalized medicine according to the clinical phenotype and genetic background of our patients; (3) to analyze digital and imaging biomarkers that predict best outcomes and select best candidates for the different therapies offered by the group.
In this call we offer a PhD Student position to study the molecular basis of SGCE myoclonus dystonia. Our group has been collecting a cohort of patients affected by this disorder and we have developed a mice model for the disease. The project will focus on studying the molecular mechanisms underlying the disease through analyzing expression methylation and location of SGCE in different tissues of mice and human. Also clinical research will be done in order to study genotypephenotype correlations and treatment response variability.
Education and qualifications:
Required:
- Bachelors Degree and Master in Biosciences related field
- Good academic records
- Good communication skills in English and Spanish
- Animal Testing and Research certification
Desired:
- Experience in clinical and/or basic research in biomedicine.
- Experience in neurosciences
Experience and knowledge:
Required:
- Experience working in common molecular techniques
- Experience working with disease mice models
- Experience in genetic analysis
- Experience in handling human biological samples
Desired:
- Strong training or handon experience in biostatistics and/or data mining
- Experience in management of databases
- Experience in cell culture
Main responsibilities and duties:
- Management of SCGE mice model colony.
- Handling processing and storage of biological samples and associated data.
- Routine and nonroutine experiments which will include molecular analysis utilizing standard techniques (DNA and RNA extraction PCR methylation assays) and histology and cell culture experiments.
- Collaborate with administrative and laboratory management tasks.
Labour conditions:
- Fulltime position: 40 hours perweek.
- Starting date: April 2025
- Gross annual salary: 19.47901
- Contract: Technical and scientific activities contract linked to the project activities.
What can we offer
- Incorporation to Vall dHebron Research Institute (VHIR) a public sector institution that promotes and develops the biomedical research innovation and teaching at Vall dHebron University Hospital (HUVH) the biggest hospital of Barcelona and the largest of Catalan Institute of Health (ICS).
- A scientific environment of excellence highly dynamic where highend biomedical projects are continuously developed.
- Continuous learning and a wide range of responsibilities within a stimulating work environment.
- Individual training opportunities.
- Flexible working hours.
- 23 days of holidays 9 personal days.
- Flexible Remuneration Program (including dining checks health insurance transportation and more)
- Corporate Benefits: platform through which you can obtain significant discounts on travel culture technology gastronomy sports... among many others.
- Healthy Offering: choose from a variety of wellbeing focused activities to be the healthiest you.
Deadline to apply:
VHIR embraces Equality and Diversity. As reflected in our values we work toward ensuring inclusion and equal opportunity in recruitment hiring training and management for all staff within the organization regardless of gender civil status family status sexual orientation gender identity and expression religion age functional diversity or ethnicity.
Employment Type
Full Time
