QC Scientist - Bioassay
QC Scientist - Bioassay
Posted on :
20-01-2025
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1 Vacancy
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Job Description
Job Title: QC Scientist Bioassay
Job Location: Hyderabad Telangana India
Job Location Type: Onsite
Job Contract Type: Fulltime
Job Seniority Level: MidSenior level
PopVax is an Indian fullstack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a nextgeneration COVID19 booster which will enter a firstinhuman Phase I clinical trial in the U.S. early this year. This vaccine is intended to broaden protection against both current and predicted future SARSCoV2 variants reducing the possibility of a new mutation in the virus suddenly causing another massive wave of infection. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNALNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10 million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organisation Balvi.
We have seen up close that there are incredible capabilities in vaccine design testing and optimization just waiting to be unlocked that will enable us to pursue and perhaps even succeed at realizing wildly ambitious agendas such as ending TB preventing future pandemics via broadlyprotective vaccines tackling the deadly scourge of antimicrobial resistance eliminating debilitating degenerative diseases like multiple sclerosis and curing fiendishly tricky chronic conditions such as ME/CFS and Long COVID. We are initiating multiple new vaccine programs this year to go after a number of these opportunities.
We are seeking a QC Scientist Bioassay to join our team in Hyderabad (note: inperson only; we do not offer remote work) to perform and document a variety of key QC assays for our mRNALNP vaccines and therapeutics.
Responsibilities will include
We have seen up close that there are incredible capabilities in vaccine design testing and optimization just waiting to be unlocked that will enable us to pursue and perhaps even succeed at realizing wildly ambitious agendas such as ending TB preventing future pandemics via broadlyprotective vaccines tackling the deadly scourge of antimicrobial resistance eliminating debilitating degenerative diseases like multiple sclerosis and curing fiendishly tricky chronic conditions such as ME/CFS and Long COVID. We are initiating multiple new vaccine programs this year to go after a number of these opportunities.
We are seeking a QC Scientist Bioassay to join our team in Hyderabad (note: inperson only; we do not offer remote work) to perform and document a variety of key QC assays for our mRNALNP vaccines and therapeutics.
Responsibilities will include
- Performing functional assays that involve transfection into mammalian cell lines and quantification of protein expression using ELISA and Western Blot.
- The use of qPCR gel electrophoresis and other molecular biologyrelated techniques for nucleic acid (i.e. pDNA and mRNA) characterization and quantification.
- The performance of compendial bioassays such as the Bacterial Endotoxins Test (BET/LAL).
- Knowledge of GDP GLP and GMP practices.
- Drafting and reviewing STPs based on analytical protocols provided by R&D teams.
- Documenting assay data and results comprehensively and precisely in a cGMPcompliant manner.
- Analyzing and interpreting assay data and results writing reports and mapping analytical trends.
- Bachelor’s or Master’s degree in Analytical Chemistry Biochemistry Microbiology Molecular Biology Cell Biology Biotechnology or a related field with 3 years of experience in performing QC assays for biologics in a cGMP setting.
- Expertise in mammalian cell culture and cellbased assays including transfection.
- Experience in the performance of ELISA assays Western Blot and gel electrophoresis.
- Proficiency in the use of word processing software such as Microsoft Word or Google Docs and spreadsheet software such as Microsoft Excel or Google Sheets for report writing data collection and basic statistical analysis.
- Excellent communication (written and oral) skills.
- An unwavering attention to detail in assay planning performance data collection and analysis.
- A deep commitment to ethical principles particularly in data collection and analysis.
- A willingness to take up new challenges in a fastpaced environment.
- Experience in qPCRbased assays for nucleic acid quantification.
- Prior experience performing assays on mRNA or DNA products.
- Knowledge of probe and primer design as relates for molecular biologyrelated assays.
- The ability to perform and document instrument validation.
- Experience in performing and documenting stability studies for biopharmaceutical products.
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Employment Type
Full Time
Key Skills
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