Drug Design Chemistry Lead London

Isomorphic Labs is a new Alphabet company that is reimagining drug discovery through a computational and AIfirst approach.

We are on a mission to accelerate the speed increase the efficacy and lower the cost of drug discovery. You'll be working at the cutting edge of the new era of 'digital biology' to deliver a transformative social impact for the benefit of millions of people.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals while being a part of an inspiring collaborative and entrepreneurial culture.

Your impact

As part of the ongoing expansion of our Drug Design and Medical Research function we are looking to recruit a new Drug Design Chemistry Lead.

You will be supporting the business alongside world leading AI/ML Drug Design Platform teams. You will collaborate to deliver scientific expertise and strategic direction to drive both improvements in the Platform and apply this to real drug design projects.

As a member of the Drug Design team you will be responsible for crossfunctional strategic alignment and effective resource allocation in support of the delivery of integrated drug discovery projects leveraging significant external CRO resources.

If you are a skilled and ambitious scientist looking to take the next step in your career joining the Isomorphic Labs now will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.

What You Will Do

• Take on a lead chemist role or project leader (depending on experience) in one or more drug discovery programs responsible for the overall chemistry strategy and compound design.
• Apply your knowledge and track record of modern drug design / discovery principals and synthetic organic chemistry to provide strategic input and technical direction to our Platform teams and to execute Drug Design programs.
• Collaborate both internally and with third party organisations interacting within multidisciplinary teams to support datadriven delivery of high quality scientific solutions to complex technical problems
• Represent the company externally interacting with existing and prospective collaborators and Contract Research Organisations (CROs)
• Manage CRO resources
• Prepare detailed scientific proposals and reports to support new and ongoing programs
• Embrace and champion our culture of inclusion and continuous professional development
  
  

Skills And Qualifications Essential

• PhD in Chemistry or a related technical field or equivalent experience
• 6 years in pharma or biotech working in different therapeutic areas
• Strong foundation in synthetic chemistry.
• Experience in execution of drug discovery programs from HitID to Candidate delivery with a consistent track record working in multidisciplinary teams
• Experience in a lead chemist role.
• Experience of contributing to StructureBased Drug Design problems
• Experience and expertise working on Lead Optimisation programs.
• Experience of working with and closely managing CRO resource
• Track record of authorship of relevant scientific manuscripts and inventorship of composition of matter patents
  
  

Nice to have:

• Experience of new modalities or peptides
  
  

Culture and values

About

What does it take to be successful at IsoLabs It's not about finding people who think and act in the same way but we do have some shared values:

Thoughtful

Thoughtful at Iso is about curiosity creativity and care. It is about good people doing good rigorous and futuremaking science every single day.

Brave

Brave at Iso is about fearlessness but it’s also about initiative and integrity. The scale of the challenge demands nothing less.

Determined

Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis as well as the urgency and agility needed to deliver on it. Because disease won’t wait so neither should we.

Together

Together at Iso is about connection collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project and remembering that what we’re doing will have a real impact on real people everywhere.

Creating An Inclusive Company

We realise that to be successful we need our teams to reflect and represent the populations we are striving to serve. We’re working to build a supportive and inclusive environment where collaboration is encouraged and learning is shared. We value diversity of experience knowledge backgrounds and perspectives and harness these qualities to create extraordinary impact.

We are committed to equal employment opportunities regardless of sex race religion or belief ethnic or national origin disability age citizenship marital domestic or civil partnership status sexual orientation gender identity pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation please do not hesitate to let us know.

Hybrid working

It’s hugely important for us to be able to share knowledge and establish relationships with each other and we find it easier to do this if we spend time together in person. This is why we’ve decided to follow a hybrid model and for full time positions we would require you to be able to come into the office 3 days a week (currently Tue Wed and one other day depending on which team you’re in). For part time positions this may vary. As an equal opportunities employer we are committed to building an equal and inclusive team. If you have additional needs that would prevent you from following this hybrid approach we’d be happy to talk through these if you’re selected for an initial screening call.

Please note that when you submit an application your data will be processed in line with our .

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