About Syngene: Syngene () is an innovationled contract research development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability including following safety guidelines procedures and SOPs in letter and spirit
Mandatory expectation for all roles as per Syngene safety guidelines
Overall adherence to safe practices and procedures of oneself and the teams aligned
Contributing to development of procedures practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
Driving a corporate culture that promotes environment health and safety (EHS) mindset and operational discipline at the workplace at all times.
Ensuring safety of self teams and lab/plant by adhering to safety protocols and following environment health and safety (EHS) requirements at all times in the workplace.
Ensure all assigned mandatory trainings related to data integrity health and safety measures are completed on time by all members of the team including self.
Compliance to Syngene’ s quality standards at all times.
Core Purpose Of The Role
To perform protein expression and purification from various expression systems
Role Accountabilities
Execution of protein expression and purification projects
Inventory management for the assigned projects
Protein expression in bacterial & mammalian cells and purification involving small & large scale batches (up to 20 L batch).
Upstream and downstream process involving bacterial and mammalian systems
Cell culture harvest filtration and protein purification
Purification of different types of tagged and nontagged proteins expertise in Affinity chromatography ionexchange chromatography hydrophobic interaction chromatography sizeexclusion chromatography analysis by SDSPAGE & Western blots
Protein refolding from Inclusion bodies and analysis of refolded protein
The candidate should be able to purify protein in a multistep purification within in speculated time limit
The candidate should maintain experimental data in ELN contemporaneously
Ability to work in a team is important and the candidate should demonstrate this objective
Syngene Values
All employees will consistently demonstrate alignment with our core values
Excellence
Integrity
Professionalism
Education: MSc or M. Pharma or M. Tech
Experience: 24 years
Technical / Functional Skills
Experience in protein expression and purification
Well versed with all the instruments required for upstream and downstream process
Should be conversant with bacterial and mammalian systems for Gene to protein projects
Execution of upstream and downstream process involving bacterial and mammalian systems
Should be conversant with SDSPAGE western blots chromatographic modes of purification using AKTA purification systems
Behavioral / Managerial Skills
Demonstrated capabilities in leading a team and working in a matrix environment. Ability to rationally discuss data make datadriven decisions and influence decisions to select optimal molecules for development. Ability to work in collaboration with a large interdisciplinary team and assimilate data from various aspects. Excellent communication and presentation skills
Experience managing multiple complex projects simultaneously requiring frequent communication organizing/time management and problemsolving skills
Excellent interpersonal communication collaboration analytical and scientific project management skills
Ability to work with senior management with professionalism and discretion
Equal Employment Opportunity
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age color national origin citizenship status physical or mental disability race religion creed gender sex sexual orientation gender identity and/or expression genetic information marital status status with regard to public assistance veteran status or any other characteristic protected by applicable legislation or local law. In addition Syngene will provide reasonable accommodations for qualified individuals with disabilities.
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