2025 Product Development Science Technology PDST Graduate Intern API Process Chemistry Late Stage

API Process Chemistry Intern (Late Stage) Overview

Envision spending your summer working with energetic colleagues and inspirational leaders all while gaining worldclass experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie Interns.

Product Development Science and Technology (PDS&T) is the intersection of technical excellence and business impact.  We are champions of product innovation and process knowledge to solve AbbVies most complex technical challenges to successfully support latephase products commercialize our pipeline ensure the quality and efficacy of our products make a direct impact on patient health and wellbeing.

As an intern on the API Process Chemistry team within the PDS&T group you will have an incredible opportunity to make a direct impact on process development optimization while gaining valuable industry experience.  The goal of this project (SulfoPBA synthesis via alternative sulfonylation chemistry and crystallization optimization) is to identify and optimize alternative synthetic approaches for an existing commercial process. The focus of this project is to use small scale experimental results and statistical modeling to identify the optimal stoichiometry and temperature range for the reaction. Further development work to improve the crystallization of the product will be performed to increase the yield of the process.  This will be followed by a proof of concept scale up batch to demonstrate the scalability of the process. The research findings from this work will be presented to the wider PDS&T group.       

Key responsibilities include:

• Receive mentoring and training to execute analytical methods experimental design and the use of statistical modeling software.
• Synthesize and isolate the starting material for the project.
• Execute a DOE to determine the optimal stoichiometry and temperature range for the reaction.
• Optimize the crystallization parameters to further improve the process yield.  
• Demonstrate the process on a 1020 g scale as proof of concept.
• Provide weekly project updates and present research findings to the department in a seminar.

Qualifications :

Minimum Qualifications 

• Currently enrolled in university pursuing a PhD in Organic Chemistry or related field.
• Must be enrolled in university for at least one semester following the internship.
• Organic synthesis experience.
• Experience with HPLC NMR and PXRD.

Preferred Qualifications

• Expected graduation date between December 2025 June 2026.

Benefits and Amenities

• Competitive pay.
• Relocation support for eligible students.
• Select wellness benefits and paid holiday / sick time.
• Exposure to industry lab setting and opportunity to develop technical expertise.

Equal Employment Opportunity
At AbbVie we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race color religion national origin age sex (including pregnancy) physical or mental disability medical condition genetic information gender identity or expression sexual orientation marital status protected veteran status or any other legally protected characteristic.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives serving our community and embracing diversity and inclusion.  It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race color religion national origin age sex (including pregnancy) physical or mental disability medical condition genetic information gender identity or expression sexual orientation marital status status as a protected veteran or any other legally protected group status.

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