Research Technician II
Research Technician II
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Job Description
Union: NonUnion
Site: Krembil Discovery Tower
Department: Schroeder Arthritis Institute
Reports to: Principal Investigator
Work Model: In Person
Grade:B0:05
Hours: 35
Salary:$30.12 37.65 per hour (To commensurate with experience and consistent with UHN compensation policy):
Shifts: n/a
Status: Temporary FullTime
Closing Date: February 28 2025
Position Summary
The Research Technician II will be responsible for handling and processing clinical samples for Health Canada authorized trials and other clinical studies. This will include immunophenotyping patient samples using flow cytometry; processing samples for other types of omic analyses. Data analyses interpretation and preparation of graphs tables and reports will also be required.
Additionally the Research Tech II will assist with animal studies including genotyping breeding weaning surgical models intraarticular injection of test therapies surgical models processing of tissues including cutting embedding staining and scoring. Experience with behavioural responses is an asset.
Duties:
- Transport samples from the fracture clinics to PIs research lab
- Immunophenotype patient samples using existing flow cytometry protocols
- Characterize heterogeneity in autologous cellular preparations with respect to growth factors protein content metabolic content as needed
- Follow SOPs and document all steps according to Good Manufacturing Practice (GMP) principles
- Analyze and interpret data including statistical analyses in collaboration with biostatistician
- Assist team members with other aspects of the clinical studies
- Maintain and breed transgenic animals
- Create intraarticular and/or surgeryinduced injury models of osteoarthritis
- Inject test therapeutics as required
- Euthanize the animals and process joint tissues for histopathological analysis in the lab
- This includes cutting embedding and sectioning block tissues staining for immunofluorescence or immunohistochemistry
- Imaging the slides
- Scoring according to standardized guidelines
Qualifications :
- BSc in Cell Biology or equivalent; MSc preferred
- Minimum 3 years related experience
- Excellent knowledge of flow cytometry including development of new protocols for cell staining and characterization
- Experience isolating and separating human cells from peripheral blood bone marrow umbilical cord and other tissues would be preferred
- Cell purification using immunomagnetic separation techniques
- Basic molecular biology skills including PCR ELISA and blotting
- Animal handling and tissue processing skills
- Immunofluorescence immunohistochemistry and/or histopathology skills
- Experience capturing animal behaviour/pain responses
- Excellent documentation skills
- Selfmotivated with strong organizational skills
- Experience with statistical software and packages
Additional Information :
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world UHN offers a wide range of benefits programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor allowing you to find value where it matters most to you now and throughout your career at UHN.
- Competitive offer packages
- Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP )
- Close access to Transit and UHN shuttle service
- A flexible work environment
- Opportunities for development and promotions within a large organization
- Additional perks (multiple corporate discounts including: travel restaurants parking phone plans auto insurance discounts onsite gyms etc.)
Current UHN employees must have successfully completed their probationary period have a good employee record along with satisfactory attendance in accordance with UHNs attendance management program to be eligible for consideration.
All applications must be submitted before the posting close date.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading inaccurate or incorrect UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest however only those selected for further consideration will be contacted.
Remote Work :
No
Employment Type :
Fulltime
Employment Type
Full-time
