drjobs Group Leader Functional Cancer Genomics

Group Leader Functional Cancer Genomics

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Job Location drjobs

Leuven - Belgium

Salary drjobs

Not Disclosed

drjobs

Salary Not Disclosed

Job Description

The VIB Center for Cancer Biology (CCB) and the KU Leuven department of Cellular and Molecular Medicine (CMM) are recruiting a group leader in Functional Cancer Genomics at located at the Campus Gasthuisberg in Leuven Belgium.

VIB is an entrepreneurial and vibrant nonprofit research institute in FlandersBelgium with a clear focus on groundbreaking research in life sciences. More than 1500 scientists and technologists from over 60 countries are working in 10 thematic research centers located at the 5 Flemish Universities of Ghent Leuven Antwerp Hasselt & Brussels and are studying the broad spectrum of molecular mechanisms that regulate the functions of the human body. VIB encourages and supports risktaking and enables collaborations with top scientists and institutes worldwide. By maintaining the highest standards of research VIB creates an innovative atmosphere and provides a supportive and collegial environment that allows the scientists to launch novel and ambitious research programs and encourages them to translate results into novel therapeutics diagnostics applications and technologies.

The VIB Center for Cancer Biology (CCB) currently hosts more than 240 scientists in 14 independent research groups and units who work on various hallmarks of tumors and their microenvironment including angiogenesis inflammation metabolism genetic epigenetic regulating circuits and cancer immunology. Together we share the ambition to contribute to a better understanding of the biology that underlies cancer initiation progression and metastatic dissemination with the ultimate goal to develop more effective and specific anticancer (combination) therapies.

The KU Leuven Department of Cellular and Molecular Medicine (CMM) encompasses 18 research groups that explore the molecular mechanisms of disease: basic cellular and molecular processes and their (patho)physiological effects as well as their implications in various human diseases. CMM combines expertise in techniques of biochemistry electrophysiology molecular biology cell imaging proteomics bioinformatics and animalmodel development to acquire novel insights into cellular signaling and communication processes. Major areas of research include signaling by ions lipids and protein phosphorylation chromatin structure and function protein structure (mis)folding and transport and cell metabolism death autophagy and differentiation.

Research

You will lead a groundbreaking scientific program addressing basic research questions with a pronounced translational potential. You have a collaborative mindset that will allow you to build bridges between existing research groups at VIB and KU Leuven as well as with other academic centers and the industry. You will focus on functional genomics with a researchspecific focus on oncology and an unmet patient need.

We are particularly interested in researchers working on the development of new technological approaches that integrate CRISPRbased technologies as well as other functional genomics or chemical biology approaches with single cell & multiomics technologies (i.e. transcriptomics proteomics metabolomics etc.). Ideally the candidate will apply these methods to reductionist (i.e. 3D tumoroid models) or unique in vivo models (i.e. mouse genetics in vivo lineage tracing PDXs…) and directly test or validate observations in these models on human tissue samples from the corresponding cancer indication.

A dedicated focus on a specific cancer indication and/or underlying biological process (metastatic dissemination lymph node involvement circulating tumor cells or specific tumor/microenvironment interactions etc. is considered a plus.

Your profile

We offer

VIB is an equalopportunity employer promoting an inclusive environment in which everyone is respected.

Expected Start date: 01st September 2025

How to apply

Please use the VIB HR application tool to upload the required documents: motivation letter full CV a twopage statement of your past achievements and future research plan list of publications and contact details of 4 referees.

Deadline to apply: 15th December 2024.

Suitable applicants will be invited to present an online seminar on their achievements and future research during March and April 2025.

For more information:

Please contact the Science Directors Diether Lambrechts or JeanChristophe Marine or the Operations Manager Michael Dewaele.

About Leuven

Leuven only 20 minutes away from Brussels by train is a vivid university city with a rich history a wellpreserved historical town center and a lively multicultural atmosphere. The city is surrounded by charming small villages woods and nature. Leuven has a lively atmosphere because of the many students from all over the world.

Leuven is home to the Universiteit Leuven the largest and oldest university in the Low Countries. The related university hospital of UZ Leuven is one of the largest hospitals in Europe. Leuven and the surroundings are a great place for young people and families to live and to raise children. There are many excellent day care centers and schools including an international school.

Employment Type

Full Time

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