Scientist

Location : IC: NIDDK Street: 8 Centre Drive Bldg.: 8 Room: 2A19 City: Bethesda State & Zip: MD 20892

Weekly Hours FT: 3040 hours per week Total No. of Hours : 40

Overall Position Summary and Objectives

Under this task order the contractor will independently provide support services to satisfy the overall operational objectives of the National Institute of Diabetes and Digestive and Kidney Diseases. The primary objective is to provide services and deliverables through performance of support services

Min Education Masters

Resume Max Pages 3

Payrate $70 hourly on W2

Certifications & Licenses

• Ph.D. in Philosophy or in another scientific field. Three (3) years of specialized experience plus a Masters degree is equivalent to a Ph.D. Five (5) years of specialized experience plus a Bachelors degree is equivalent to a Ph.D.
• Minimum of five (5) years of experience in a science related field

Skills (Ranked by Priority)

1. Excellent analytical organizational and time management skills
2. Demonstrate expertise in the generation and analysis of mouse model pluripotent stem cell culture and differentiation
3. Significant scientific training in the areas of mouse and human genetics stem cell biology flow cytometry DNA and protein purification the genetics of repeat expansion mutations and their analysis
4. Strong publication record.
5. Strong communications skills both oral and written

1 2 3 4 5 represents priority rankings where 1 is highest priority and 5 is lowest priority of those ranked

Software

• MS Office Suite
• Graphpad Prism

Field of Study

• Miscellaneous Biology
• Molecular Biology
• Genetics
• Biochemical Sciences

Statement of Work Details

Provides technical experience needed to assist in studying the basic principles of plant and animal life

• Study basic principles of plant and animal life such as origin relationship development anatomy and function
• Identify classify and study structure behaviour ecology physiology nutrition culture and distribution of plant and animal species
• Plan and conduct biological research programs

Assists with performing basic laboratory experiments and procedures

• Monitor biological technicians and technologists and other scientists
• Monitor and observe experiments recording production and test data for evaluation by research personnel
• Analyze experimental data and interpret results to write reports and summaries of findings

Prepares organizes and maintains various lab samples supplies and equipment

• Maintain laboratory equipment
• Analyze laboratory findings

Learns new laboratory techniques and procedures

• Program and use computers to store process and analyze data
• Interpret research or operational data
• Record research or operational data

Other

• Be responsible for the management of the Usdin Laboratory mouse colony. This work includes maintaining stocks of essential mouse strains coordinating the import of additional mice into the mouse colony and the export of mice/mouse embryos/mouse sperm to other facilities as needed ensuring the cryopreservation and cryorecovery of appropriate mouse lines develop appropriate genotyping assays for new mouse lines supervising the generation of new mouse lines both by CRISPRmediated geneediting of embryos and appropriate breeding strategies using preexisting mutant mice overseeing CRISPRmediated geneediting of embryos and appropriate breeding strategies using preexisting mutant mice overseeing the generation of embryonic stem cell and embryonic fibroblasts derived from these animals design and prepare animal study protocols and standard operation procedures (SOPs)
• Train new personnel in appropriate labapproved SOPs including those in place for working with this animal colony
• Maintain and coordinate scientific equipment and make recommendations where necessary for the acquisition of new equipment
• Conduct research on the molecular mechanisms responsible for mutation and disease pathology in the Repeat Expansion Disorders with a focus on the Fragile Xrelated disorder Friedreich ataxia and GLC Deficiency.
• Perform research using genetic mouse and cellular models.
• Develop reagents assays and methodology that contribute to the goal of moving all the projects in the laboratory forward.
• Maintain records of the experiments performed and the data acquired; update and maintain laboratory notebooks and databases.
• Perform scientific literature searches.
• Prepare reports on the experimental design notes and progress of research programs studies and trials.
• Prepare experimental results including images blots expression data etc.
• Coordinate multiple projects concurrently in progress.
• Collaborate with other research staff to ensure continuity of progress.
• Participate in the weekly intergroup lab meetings and present research update as appropriate
• Produce presentation slides for meetings
• Prepare manuscripts and submit research papers to peerreviewed scientific journals
• Attend scientific meetings and represent the lab in poster and oral presentations as opportunity arises
• Contribute to collaborative projects not only with other members within the lab but also with other laboratories as opportunity arises
• Organize daily laboratory notebook on experiments
• Prepare biweekly updates on ongoing experiments and tasks and present progress reports on assigned projects at group meetings
• Assist with Postbac recruitment onboarding and training
• Coordinate and maintain LabArchives account at NIDDK