Sr Director of Project Management

About Evrys Bio:

This is an opportunity to join a small entrepreneurial and wellfunded private biotech company. Building on research breakthroughs from an internationally renowned scientific team our research platform has enabled us to discover new antiviral drugs with a different mechanistic approach that will change the way infection is treated from one virus at a time to broadspectrum therapies simultaneously effective against different viruses without the emergence of drug resistance. Evrys Bio antivirals target special human proteins known as sirtuins enhancing their natural ability to fight powerful infections. The company is funded by private investors and by multimilliondollar government grants and contracts to develop therapies addressing infection control pandemic preparedness and biodefense.

We are searching for an experienced and dynamic hands on Director or Sr. Director Project Management with a preference for someone with a scientific background as well as proven experience in advancing preclinical and clinical development programs in the biotech industry. In this key role the successful highly organized candidate will lead the work and budget for our main development asset EV100 that is targeting an IND in Q4/2024. They will also lead the engagement with the DOD our government sponsor to assure that we meet our goals and report our progress and budget utilization accordingly. Used to working in a nimble biotech environment the successful candidate knows how to get things done plans for contingencies is comfortable at facing and helping the team overcome development challenges. They will play a pivotal role in advancing our overall project management capabilities.

With COVID19 and its variants we ve become more aware than ever of the need for novel antiviral therapies. So have government agencies who fund medical research as well as large pharmaceutical corporations looking for the next big cure. Our scientific team has seen hundreds of viruses emerge for which there is no known effective drug therapy and in some cases resistance is building against existing drugs. Hence key elements of our team culture are a sense of thoughtful urgency and collaboration. We have made significant advances recently and are progressing towards initiating clinical studies in the next 18 months. This creates a big opportunity to make a difference for us and in turn this may present career growth opportunities for the right candidate.

This position reports to the Head of Operations and Strategy (member of the executive leadership team) with frequent interactions with our CEO CFO and VP of Research. The position is based @ the Company s Doylestown PA Headquarters.

Key Responsibilities:

Lead the late preclinical and early clinical development of EV100 our small molecule lead candidate for respiratory infections.
o Matrix lead for an array of top notch internal and external collaborators (preclinical CMC consultants) as well as vendors (CDMO CRO etc.)

o Keep the team on track to deliver on an IND and initiate clinical studies by EOY 2024
o Assure that the relevant voices are heard
o Ability to occasionally travel to a partner when required
Manage the budget and monthly reporting for our government sponsor
Closely partner with all business segments to help align vendor performance in accordance with contractual agreements.
Collaborate with our research department to align on progress and processes for the discovery work including backup / next generation compounds

Participate in key crossfunctional corporate meetings to advance corporate goals contractual workstreams
Help advance the Evrys corporate culture and skill set

Requirements

Qualifications and Skills for the job:

12 years of progressive leadership positions in the biotech industry in similar positions managing key early development and early clinical programs

o Thorough understanding of the key processes and requirements to deliver an IND and clinical studies

Understands key challenges helps anticipate and mitigate these

Good understanding of regulatory processes

o Plans thoughtfully and executes the plan

o Demonstrated ability to deliver programs through teams

Skilled at collaborating in a matrix environment with a diverse group of stakeholders

Impact through influence

Experienced at working with and managing external partners and keeping everybody on track e.g CDMO external preclinical CRO s clinical CRO s

o Manages the overall budget

o Skilled at managing and tracking contractual aspects of key vendors in the biotech value chain.

o Looks around corners plans for contingencies

o Negotiates key contracts collaborates with legal to implement in the best form for the company

A highly organized hands on planner and doer with a positive can do mentality

o Skilled at project management tracking and reporting

Experiences at collaborating with NIH Grant and DoD Contracts as sponsors highly desirable

Preference for someone with a scientific background and an MBA or PMP

Experience in the respiratory field a plus

Comfortable in working in fast paced and growing operational biotech environment

Very good written and verbal communication skills.

Skilled with MS Word Excel MS Project or similar platform

Ambitious with desire to learn & grow

Contributes to a highenergy fullyengaged positive accountable team culture described in E.V.R.Y.S. success behaviors and values

12+ years of progressive leadership positions in the biotech industry in similar positions, managing key early development and early clinical programs o Thorough understanding of the key processes and requirements to deliver an IND and clinical studies Understands key challenges, helps anticipate and mitigate these Good understanding of regulatory processes o Plans thoughtfully and executes the plan o Demonstrated ability to deliver programs through teams, Skilled at collaborating in a matrix environment with a diverse group of stakeholders, Impact through influence Experienced at working with and managing external partners and keeping everybody on track e.g CDMO, external preclinical CRO s, clinical CRO s o Manages the overall budget o Skilled at managing and tracking contractual aspects of key vendors in the biotech value chain. o Looks around corners, plans for contingencies o Negotiates key contracts, collaborates with legal to implement in the best form for the company A highly organized hands on planner and doer with a positive can do mentality o Skilled at project management, tracking and reporting Experiences at collaborating with NIH Grant and DoD Contracts as sponsors highly desirable Preference for someone with a scientific background, and an MBA or PMP Experience in the respiratory field a plus Comfortable in working in fast paced and growing operational biotech environment, Very good written and verbal communication skills. Skilled with MS Word, Excel, MS Project or similar platform Ambitious, with desire to learn & grow