Postdoctoral researcher to study the role of Tau MEG3 and necroptosis in Alzheimers Disease
صاحب العمل نشط
حالة تأهب وظيفة
سيتم تحديثك بأحدث تنبيهات الوظائف عبر البريد الإلكتروني
شارك هذه الوظيفة
حالة تأهب وظيفة
سيتم تحديثك بأحدث تنبيهات الوظائف عبر البريد الإلكتروني
الوصف الوظيفي
Description
Additional information may be found in the following selected references from the lab:
- Xenografted human microglia display diverse transcriptomic states in response to Alzheimers diseaserelated amyloid pathology. Nat Neurosci. 2024. PMID:
- MEG3 activates necroptosis in human neuron xenografts modeling Alzheimers disease. Science. 2023 Sep 15;381(6663):. PMID:
- The Cellular Phase of Alzheimers Disease. Cell 164(4):60315. 2016. PMID: Review.
Profile
Required
The successful candidate:
- Should hold a PhD degree in neuroscience biology or a related field
- Should be creative enthusiastic and critically thinking
- Enjoys teamwork and has excellent oral and written communication skills in English.
Appreciated
- Experience working with laboratory mice
- Project management and effective communication skills
- Knowledge of the literature on neurodegenerative disorders
- Knowledge of noncoding RNA
- Good understanding of the endolysosomal pathway
- Experience working with iPSC cells
- Good publication record
We offer
- An exceptionally strong scientific environment
- Possibility to supervise students and technicians and develop an independent research profile
- Access to stateoftheart infrastructure
- A stimulating diverse international research environment in a worldclass academic laboratory
- Animal models expertise in neurodegenerative disorders
- Financial support is available for at least 2 years (renewable oneyear contract). However the successful candidate is encouraged to obtain a personal fellowship (MarieCurie HFSP EMBO or National funding organizations).
- Start date: as soon as possible the position is available immediately
How to apply
Motivated candidates with a strong interest in neurodegeneration and with a strong commitment to basic research are invited to apply. Please complete the online application procedure and include a CV a list of publications a summary of past research and the contact information of 2 to 3 referees. The bestranked candidates will be invited for an interview.
For additional information concerning this position please contact Bart De Strooper ().
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