Research Associate

We are is using a novel glycan engineering approach to deliver better therapeutics to

those most in need. We engineer drugs by controlling the addition of glycans essential

sugar molecules found on the surface of drugs to enhance drug specificity activity and

longevity. We have developed a proprietary technology to control the glycans added to

drugs and have a patent pending.

We are a dynamic international earlystage startup backed by Entrepreneur First the

worlds leading talent investor along with European and US investors. We have

established collaborations with KOLs across the globe and is advised by leading professors in

the field and a former Sanofi VP. We have recently won numerous prestigious research

grants including the iLab Concours dInnovation (BPI France) the Women TechEU (European

Innovation Commission) and Innovup Leader PIA (BPI France).

Tasks

You will work directly with the Senior Scientist in a dynamic role taking on various projects

and tasks. The role involves a mixture of research and bench work. Your main functions will

include:

Producing and analyzing recombinant therapeutic proteins from our CHO cell panel

Optimizing protein expression in our CHO cell lines coordinating with third parties

where required

Quality reporting of cell banks

Identifying collaborators and KOLs from scientific articles conferences and

networking and leading discussions with them

Establishing and managing collaborations with academic groups

6 rue Jean Calvin 75005 Paris France

Analyzing competitive landscapes including patent literature

Contributing to set up and development of inhouse analytical studies

Providing insights and recommendations for strategic decision making

Supporting in expanding out our laboratory facilities

Requirements

PhD in cell and molecular biology biochemistry biological engineering or other life

science discipline

Experience in CHO cell line culture and development which includes:

o Vector design and cloning; Stable and transient transfections; Single cell clone

selection (FACS or serial dilutions); Research Cell Banking (RCB) generation; Cell

line stability assessment studies; Genetic characterization methods (qPCR whole

genome sequencing)

Experience in recombinant monoclonal antibody production and purification which

includes:

o Cell supernatant harvesting and clarifying; Titer measurements (ELISA/Octet);

Antibody purification (affinity and gel filtration chromatography); Protein sample

prep for downstream analysis (buffer exchange concentrating); in vitro and cell

based activity assays (antigen binding ADCC activity etc.)

Entrepreneurial mindset:

o As an earlystage startup we need someone who can adapt quickly to shifting

priorities take initiative and be proactive in contributing to the success of the

team

Fluency in English

Excellent command of scientific literature and writing skills

Ability to multitask and manage multiple projects simultaneously

Exceptional organizational skills

Ability to think in a creative manner to solve problems a strong bias to action

Able to work in a timely manner to meet tight deadlines

Quick learner and eager to take on new tasks outside of comfort zone

Great communication skills and open to both giving and receiving feedback

A team player who is strongly invested in our mission and is excited to

get involved in all aspects of company building

Benefits

Opportunity to be a member of the founding team of an innovative startup

Work directly with the Senior Scientist in our dynamic R&D team in the center of

Paris: our labs are based at the IPGG in Paris 5me right off Rue Mouffetard!

Competitive research salary

Employee first mentality. We will do everything we can for employee mental and

physical health. Down time will be respected. Annual leave will be generous. Breaks

are strongly encouraged. Rest is an essential component of productivity!

The opportunity to help bring advanced drugs to the market improving the lives of

millions of people

We are committed to building a diverse and inclusive workplace. We welcome

applications from people from all walks of life.